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Showing posts with the label muscarine

Drug Overdose and Poisoning

 Poisoning of some Drugs poisoning caused by some drugs and how to deal with them 1. Poisoning with muscarine: Symptoms:   miosis,  blurred vision,  increased salivation,  excessive sweating,  lacrimation,  bronchial secretions,  bronchoconstriction,  bradycardia,  abdominal cramping,  increased gastric acid secretion,  diarrhea and polyuria (it might cause also tremor, convulsions and hypothermia). Miosis A s we all are well aware that muscarine is a acetylcholine agonist which in turn stimulates the cholinergic receptors which are an integral part of Parasympathetic post synaptic receptors and sympathetic sweat receptors all are triggered by acetyl choline agonist muscarine leading to all the above mentioned symptoms and so to treat it we use a Acetylcholine Antagonist which block the channels that are being stimulated leading to the blockage of all the response of the choline related reactions. Treatment:  The dru...