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Showing posts with the label amides

Local Anesthesia

all the local anesthetics are Basic Drugs  local anesthetics cross the membrane in non ionized  for and block the Na channels in ionized  form  local anesthetics are of 2 types  Ester and Amide but the name of both type of local anesthetics end with  CAINE [ad]   mechanism of action of local anesthesia   Ester                                      Amide  cocaine                                     lignocaine procaine                                         bupivacaine chlorprocaine                            prilocaine  tetracaine                                 Etidocaine     benzocaine                                ropivacaine                                                  Dibucaine So What is the significance of amide and ester and why should we always keep in mind which is ester and which is amide?? ans-   we should always remember which group is ester an