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Showing posts with the label central muscle relaxants

Skeletal Muscle Relaxatants and reversal agents

Skeletal Muscle Relaxants So we have 2 types of muscle relaxants:- Those which work on the CNS ( Central ) those who work on the muscle and their NM receptors (peripheral) Central Muscle Relaxant So to use center in material relaxants we need a drug which stimulates the receptors present in the CNS and such receptors are          GABA a receptors – Diazepam      GABA b   receptors --- Baclofen      alpha 2 receptors(acts like break )- t izanidine      Another group of centrally acting muscle relaxants are those which act by inhibiting the polysynaptic reflexes examples - Mephensin ,Chlorzoxazone, thiocolchicoside   Peripheral muscle relaxants there are two types:-   directly acting and indirectly acting Directly acting :-   they directly act on the muscles d irectly acting-dantrolene :- works by blocking ryanodine receptor in endoplasmic reticulum from muscles Ryanodine receptor...